Multiple Oral Mucosal Neuromas: A Case Report of Multiple Endocrine Neoplasia Type 2B Patient
이동우, 홍유진, 권태건, 최소영,
소속 상세정보
이동우 ( Lee Dong-Woo ) - Kyungpook National University School of Dentistry Department of Oral and Maxillofacial Surgery
홍유진 ( Hong Yoo-Jin ) - Kyungpook National University School of Dentistry Department of Oral and Maxillofacial Surgery
권태건 ( Kwon Tae-Geon ) - Kyungpook National University School of Dentistry Department of Oral and Maxillofacial Surgery
최소영 ( Choi So-Young ) - Kyungpook National University School of Dentistry Department of Oral and Maxillofacial Surgery
Abstract
Multiple endocrine neoplasia type 2B (MEN2B), which is an autosomal dominant hamartoneoplastic syndrome, is a genetic syndrome. Patients with this syndrome are characterized by multiple mucosal neuromas on the tongue, lips, eyelid margins, and conjunctiva with marfanoid habitus, thick and protruding lips, open bite, and maxillary central diastema. Multiple oral mucosal neuromas are known to appear before the development of medullary thyroid carcinoma (MTC) or pheochromocytoma. Therefore, understanding the oral symptoms is very important for the early diagnosis of this syndrome. We report multiple submucosal neuromas in a 19-year-old male patient diagnosed with MEN2B and review this syndrome.
키워드
Multiple oral mucosal neuromas; Multiple endocrine neoplasia type 2B; Medullary thyroid carcinoma
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